Exosomal miR-130b-3p Promotes Progression and Tubular Formation Through Targeting PTEN in Oral Squamous Cell Carcinoma

Exosomal miR-130b-3p Promotes Progression and Tubular Formation Through Targeting PTEN in Oral Squamous Cell Carcinoma

Oral squamous cell carcinoma (OSCC), accounting for two-thirds of head and neck cancer, is characterized by poor prognosis and a high rate of mortality. Exosomes have emerged as potential molecule-shuttle in intercellular communication, thereby regulating the physiological processes of recipient cel...

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Bibliographic Details
Main Authors: Wei Yan, Yuping Wang, Yong Chen, Yanjun Guo, Qiang Li, Xiaotong Wei
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
oral squamous cell carcinoma
exosome
miR-130b-3p
progression
Pten
tubular formation
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.616306/full

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