Antimicrobial Activity of Geranium Oil against Clinical Strains<em> </em>of <em>Staphylococcus aureus</em>

• Main Authors: Monika Sienkiewicz, Danuta Kalemba, Małgorzata Wasiela, Monika Bigos
• Format: Article
• Language: English
• Published: MDPI AG 2012-08-01
• Series: Molecules
• Subjects: antibacterial activity; geranium oil; MIC; multidrug resistant strains; <em>Staphylococcus aureus</em>
• Online Access: http://www.mdpi.com/1420-3049/17/9/10276

The aim of this work was to investigate the antibacterial properties of geranium oil obtained from <em>Pelargonium graveolens</em> Ait. (family <em>Geraniaceae</em>), against one standard <em>S. aureus </em>strain ATCC 433000 and seventy clinical <em>S. aureus</em> strains. The agar dilution method was used for assessment of bacterial growth inhibition at various concentrations of geranium oil. Susceptibility testing of the clinical strains to antibiotics was carried out using the disk-diffusion and E-test methods. The results of our experiment showed that the oil from <em>P. graveolens</em> has strong activity against all of the clinical <em>S. aureus</em> isolates—including multidrug resistant strains, MRSA strains and MLS<sub>B</sub>-positive strains—exhibiting MIC values of 0.25–2.50 μL/mL.