Radical curative efficacy of tafenoquine combination regimens in <it>Plasmodium cynomolgi</it>-infected Rhesus monkeys (<it>Macaca mulatta</it>)

Radical curative efficacy of tafenoquine combination regimens in <it>Plasmodium cynomolgi</it>-infected Rhesus monkeys (<it>Macaca mulatta</it>)

<p>Abstract</p> <p>Background</p> <p>Tafenoquine is an 8-aminoquinoline being developed for radical cure (blood and liver stage elimination) of <it>Plasmodium vivax</it>. During monotherapy treatment, the compound exhibits slow parasite and fever clearance t...

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Main Authors: Kenworthy David, Milhous Wilbur, Cozens Simon, Kyle Dennis, Sattabongkot Jetsumon, Komcharoen Srawuth, Imerbsin Rawiwan, Hansukjariya Pranee, Gettayacamin Montip, Dow Geoffrey S, Miller Anne, Veazey Jim, Ohrt Colin
Format: Article
Language:English
Published: BMC 2011-07-01
Series:Malaria Journal
Online Access:http://www.malariajournal.com/content/10/1/212

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