Nonrandom Distribution of Azole Resistance across the Global Population of Aspergillus fumigatus

Nonrandom Distribution of Azole Resistance across the Global Population of Aspergillus fumigatus

Azole drug resistance in the human-pathogenic fungus Aspergillus fumigatus continues to emerge, potentially leading to untreatable aspergillosis in immunosuppressed hosts. Two dominant, environmentally associated resistance mechanisms, which are thought to have evolved through selection by the agric...

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Bibliographic Details
Main Authors: Thomas R. Sewell, Jianing Zhu, Johanna Rhodes, Ferry Hagen, Jacques F. Meis, Matthew C. Fisher, Thibaut Jombart
Format: Article
Language:English
Published: American Society for Microbiology 2019-05-01
Series:mBio
Subjects:
Aspergillus fumigatus
antifungal chemicals
azole resistance
fungal pathogen
fungicides
global distribution
Online Access:https://doi.org/10.1128/mBio.00392-19

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