Synthesis and in vitro anti-HIV-1 evaluation of some N-arylsulfonyl-3-formylindoles

Synthesis and in vitro anti-HIV-1 evaluation of some N-arylsulfonyl-3-formylindoles

As our ongoing work on research of anti-HIV-1 inhibitors, fifteen N-arylsulfonyl-3-formylindoles (3a-o) were designed and prepared through two step synthetic route. Firstly, 3-formylindoles (2a-c) were synthesized via the Vilsmeier-Haack reaction. Subsequently, treatment of 2a-c with the appropriate...

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Bibliographic Details
Main Authors:	Zhiping Che, Yuee Tian, Shengming Liu, Mei Hu, Genqiang Chen
Format:	Article
Language:	English
Published:	Universidade de São Paulo 2018-11-01
Series:	Brazilian Journal of Pharmaceutical Sciences
Subjects:	N-Arylsulfonyl-3-formylindole/synthesis Human immunodeficiency virus type-1/inhibitor
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000300605&lng=en&tlng=en

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