Unfractionated heparin attenuates endothelial barrier dysfunction via the phosphatidylinositol-3 kinase/serine/threonine kinase/nuclear factor kappa-B pathway

Unfractionated heparin attenuates endothelial barrier dysfunction via the phosphatidylinositol-3 kinase/serine/threonine kinase/nuclear factor kappa-B pathway

Abstract. Background. Vascular endothelial dysfunction is considered a key pathophysiologic process for the development of acute lung injury. In this study, we aimed at investigating the effects of unfractionated heparin (UFH) on the lipopolysaccharide (LPS)-induced changes of vascular endothelial-c...

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Bibliographic Details
Main Authors: Sheng-Tian Mu, Jie Tang, Jian-Qi Ma, Yu Zhong, Han-Zhe Liu, Xiao-Chun Ma, Zhen Zheng, Qiang Shi
Format: Article
Language:English
Published: Wolters Kluwer 2020-08-01
Series:Chinese Medical Journal
Online Access:http://journals.lww.com/10.1097/CM9.0000000000000905

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