A review of experimental models of focal cerebral ischemia focusing on the middle cerebral artery occlusion model [version 1; peer review: 2 approved]

Cerebral ischemic stroke is a leading cause of death and disability, but current pharmacological therapies are limited in their utility and effectiveness. In vitro and in vivo models of ischemic stroke have been developed which allow us to further elucidate the pathophysiological mechanisms of injur...

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Bibliographic Details
Main Authors: Melissa Trotman-Lucas, Claire L. Gibson
Format: Article
Language:English
Published: F1000 Research Ltd 2021-03-01
Series:F1000Research
Online Access:https://f1000research.com/articles/10-242/v1