Vitamin D status is positively correlated with regulatory T cell function in patients with multiple sclerosis.

In several autoimmune diseases, including multiple sclerosis (MS), a compromised regulatory T cell (Treg) function is believed to be critically involved in the disease process. In vitro, the biologically active metabolite of vitamin D has been shown to promote Treg development. A poor vitamin D stat...

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Bibliographic Details
Main Authors: Joost Smolders, Mariëlle Thewissen, Evelyn Peelen, Paul Menheere, Jan Willem Cohen Tervaert, Jan Damoiseaux, Raymond Hupperts
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2721656?pdf=render

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