Ladder-Shaped Ion Channel Ligands: Current State of Knowledge

Ladder-Shaped Ion Channel Ligands: Current State of Knowledge

Ciguatoxins (CTX) and brevetoxins (BTX) are polycyclic ethereal compounds biosynthesized by the worldwide distributed planktonic and epibenthic dinoflagellates of Gambierdiscus and Karenia genera, correspondingly. Ciguatera, evoked by CTXs, is a type of ichthyosarcotoxism, which involves a variety o...

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Bibliographic Details
Main Authors:	Yuri B. Shmukler, Denis A. Nikishin
Format:	Article
Language:	English
Published:	MDPI AG 2017-07-01
Series:	Marine Drugs
Subjects:	ciguatoxin maitotoxin brevetoxin brevenol voltage-gated Na+-channel thylakoid membrane light-harvesting complex II
Online Access:	https://www.mdpi.com/1660-3397/15/7/232

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