Pathogenesis of cholestasis-induced liver fibrosis and thoughts for blockade

Cholestasis refers to a pathological state of disorders in the formation, secretion, and excretion of bile flow, and liver fibrosis is a process of tissue repair induced by liver injury. Cholestatic liver disease is a chronic liver disease caused by cholestasis, progressive bile duct injury, and per...

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Main Author: CHEN Ruiling
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Hepatology 2019-02-01
Series:Linchuang Gandanbing Zazhi
Online Access:http://www.lcgdbzz.org/qk_content.asp?id=9584
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spelling doaj-4606eda0e994490a83d28ea29a9de3de2020-11-24T21:19:01ZzhoEditorial Department of Journal of Clinical HepatologyLinchuang Gandanbing Zazhi1001-52561001-52562019-02-01352247251Pathogenesis of cholestasis-induced liver fibrosis and thoughts for blockadeCHEN Ruiling0Department of Gastroenterology, Renji Hospital, Shanghai Jiao Tong University School of Medicine & Shanghai Institute of Digestive Diseases, Shanghai 200001, ChinaCholestasis refers to a pathological state of disorders in the formation, secretion, and excretion of bile flow, and liver fibrosis is a process of tissue repair induced by liver injury. Cholestatic liver disease is a chronic liver disease caused by cholestasis, progressive bile duct injury, and persistent intrahepatic inflammation, and it may cause cholangiocyte and hepatocyte injury, which will gradually progress to liver fibrosis. With reference to the current research advances, this article reviews the pathogenesis of cholestasis-induced liver fibrosis and the strategies for blockade.http://www.lcgdbzz.org/qk_content.asp?id=9584
collection DOAJ
language zho
format Article
sources DOAJ
author CHEN Ruiling
spellingShingle CHEN Ruiling
Pathogenesis of cholestasis-induced liver fibrosis and thoughts for blockade
Linchuang Gandanbing Zazhi
author_facet CHEN Ruiling
author_sort CHEN Ruiling
title Pathogenesis of cholestasis-induced liver fibrosis and thoughts for blockade
title_short Pathogenesis of cholestasis-induced liver fibrosis and thoughts for blockade
title_full Pathogenesis of cholestasis-induced liver fibrosis and thoughts for blockade
title_fullStr Pathogenesis of cholestasis-induced liver fibrosis and thoughts for blockade
title_full_unstemmed Pathogenesis of cholestasis-induced liver fibrosis and thoughts for blockade
title_sort pathogenesis of cholestasis-induced liver fibrosis and thoughts for blockade
publisher Editorial Department of Journal of Clinical Hepatology
series Linchuang Gandanbing Zazhi
issn 1001-5256
1001-5256
publishDate 2019-02-01
description Cholestasis refers to a pathological state of disorders in the formation, secretion, and excretion of bile flow, and liver fibrosis is a process of tissue repair induced by liver injury. Cholestatic liver disease is a chronic liver disease caused by cholestasis, progressive bile duct injury, and persistent intrahepatic inflammation, and it may cause cholangiocyte and hepatocyte injury, which will gradually progress to liver fibrosis. With reference to the current research advances, this article reviews the pathogenesis of cholestasis-induced liver fibrosis and the strategies for blockade.
url http://www.lcgdbzz.org/qk_content.asp?id=9584
work_keys_str_mv AT chenruiling pathogenesisofcholestasisinducedliverfibrosisandthoughtsforblockade
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