Pathogenesis of cholestasis-induced liver fibrosis and thoughts for blockade
Cholestasis refers to a pathological state of disorders in the formation, secretion, and excretion of bile flow, and liver fibrosis is a process of tissue repair induced by liver injury. Cholestatic liver disease is a chronic liver disease caused by cholestasis, progressive bile duct injury, and per...
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Editorial Department of Journal of Clinical Hepatology
2019-02-01
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doaj-4606eda0e994490a83d28ea29a9de3de2020-11-24T21:19:01ZzhoEditorial Department of Journal of Clinical HepatologyLinchuang Gandanbing Zazhi1001-52561001-52562019-02-01352247251Pathogenesis of cholestasis-induced liver fibrosis and thoughts for blockadeCHEN Ruiling0Department of Gastroenterology, Renji Hospital, Shanghai Jiao Tong University School of Medicine & Shanghai Institute of Digestive Diseases, Shanghai 200001, ChinaCholestasis refers to a pathological state of disorders in the formation, secretion, and excretion of bile flow, and liver fibrosis is a process of tissue repair induced by liver injury. Cholestatic liver disease is a chronic liver disease caused by cholestasis, progressive bile duct injury, and persistent intrahepatic inflammation, and it may cause cholangiocyte and hepatocyte injury, which will gradually progress to liver fibrosis. With reference to the current research advances, this article reviews the pathogenesis of cholestasis-induced liver fibrosis and the strategies for blockade.http://www.lcgdbzz.org/qk_content.asp?id=9584 |
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DOAJ |
language |
zho |
format |
Article |
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DOAJ |
author |
CHEN Ruiling |
spellingShingle |
CHEN Ruiling Pathogenesis of cholestasis-induced liver fibrosis and thoughts for blockade Linchuang Gandanbing Zazhi |
author_facet |
CHEN Ruiling |
author_sort |
CHEN Ruiling |
title |
Pathogenesis of cholestasis-induced liver fibrosis and thoughts for blockade |
title_short |
Pathogenesis of cholestasis-induced liver fibrosis and thoughts for blockade |
title_full |
Pathogenesis of cholestasis-induced liver fibrosis and thoughts for blockade |
title_fullStr |
Pathogenesis of cholestasis-induced liver fibrosis and thoughts for blockade |
title_full_unstemmed |
Pathogenesis of cholestasis-induced liver fibrosis and thoughts for blockade |
title_sort |
pathogenesis of cholestasis-induced liver fibrosis and thoughts for blockade |
publisher |
Editorial Department of Journal of Clinical Hepatology |
series |
Linchuang Gandanbing Zazhi |
issn |
1001-5256 1001-5256 |
publishDate |
2019-02-01 |
description |
Cholestasis refers to a pathological state of disorders in the formation, secretion, and excretion of bile flow, and liver fibrosis is a process of tissue repair induced by liver injury. Cholestatic liver disease is a chronic liver disease caused by cholestasis, progressive bile duct injury, and persistent intrahepatic inflammation, and it may cause cholangiocyte and hepatocyte injury, which will gradually progress to liver fibrosis. With reference to the current research advances, this article reviews the pathogenesis of cholestasis-induced liver fibrosis and the strategies for blockade. |
url |
http://www.lcgdbzz.org/qk_content.asp?id=9584 |
work_keys_str_mv |
AT chenruiling pathogenesisofcholestasisinducedliverfibrosisandthoughtsforblockade |
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1726007250148917248 |