Impact of Cytomegalovirus Infection and Genetic Background on the Frequencies of Peripheral Blood Suppressor Cells in Human Twins

Impact of Cytomegalovirus Infection and Genetic Background on the Frequencies of Peripheral Blood Suppressor Cells in Human Twins

Frequencies and proportions of regulatory T cells (Tregs) and myeloid-derived suppressor cells (MDSCs) in peripheral blood may be informative biomarkers for certain disease states. The influence of genetics and lifetime pathogen exposures on Treg and MDSC frequencies is largely unexplored. Cytomegal...

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Bibliographic Details
Main Authors: David Goldeck, Lisbeth Aagaard Larsen, Kaare Christensen, Klaus Hamprecht, Lilly Öttinger, Karin Hähnel, Graham Pawelec
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Pathogens
Subjects:
cytomegalovirus
regulatory T cells
myeloid-derived suppressor cells
twins
heritability
genetics
Online Access:https://www.mdpi.com/2076-0817/10/8/963

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