Sensory neurons expressing calcitonin gene-related peptide α regulate adaptive thermogenesis and diet-induced obesity

Sensory neurons expressing calcitonin gene-related peptide α regulate adaptive thermogenesis and diet-induced obesity

Objectives: Heat-sensory neurons from the dorsal root ganglia (DRG) play a pivotal role in detecting the cutaneous temperature and transmission of external signals to the brain, ensuring the maintenance of thermoregulation. However, whether these thermoreceptor neurons contribute to adaptive thermog...

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Bibliographic Details
Main Authors: Kuldeep Makwana, Harshita Chodavarapu, Nancy Morones, Jingyi Chi, William Barr, Edward Novinbakht, Yidan Wang, Peter Tuan Nguyen, Predrag Jovanovic, Paul Cohen, Celine E. Riera
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Molecular Metabolism
Subjects:
CGRP
Spinal sensory ganglion
Energy expenditure
Obesity
Thermoregulation
Lipolysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877821000016

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http://www.sciencedirect.com/science/article/pii/S2212877821000016

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