Molecular Mechanisms Regulating Hepcidin Revealed by Hepcidin Disorders

Iron is essential for human life, but toxic if present in excess. To avoid iron overload and maintain iron homeostasis, all cells are able to regulate their iron content through the post-transcriptional control of iron genes operated by the cytosolic iron regulatory proteins that interact with iron...

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Bibliographic Details
Main Authors: Clara Camaschella, Laura Silvestri
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2011.130