Design of Deterministic Model of Signal Transduction between Neuronal Cells
Mathematical model describing signal transduction between neurons has been presented using the system of nonlinear ordinary differential equations. The Cauchy problem for the given system has been solved numerically and system parameters were adjusted to match the results of experimental measuremen...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Vilnius Gediminas Technical University
2015-02-01
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| Series: | Mathematical Modelling and Analysis |
| Subjects: | |
| Online Access: | https://journals.vgtu.lt/index.php/MMA/article/view/985 |
| Summary: | Mathematical model describing signal transduction between neurons has been presented using the system of nonlinear ordinary differential equations. The Cauchy problem for the given system has been solved numerically and system parameters were adjusted to match the results of experimental measurements of extracellular postsynaptic potentials in rat hippocampus slices. While fitting model to the experimental data some values of synaptic parameters have been determined.
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| ISSN: | 1392-6292 1648-3510 |