Heating Efficiency of Triple Vortex State Cylindrical Magnetic Nanoparticles

Abstract A well-established method for treating cancerous tumors is magnetic hyperthermia, which uses localized heat generated by the relaxation mechanism of magnetic nanoparticles (MNPs) in a high-frequency alternating magnetic field. In this work, we investigate the heating efficiency of cylindric...

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Main Authors: De Wei Wong, Wei Liang Gan, Yuan Kai Teo, Wen Siang Lew
Format: Article
Language:English
Published: SpringerOpen 2019-12-01
Series:Nanoscale Research Letters
Subjects:
Online Access:https://doi.org/10.1186/s11671-019-3169-6
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spelling doaj-45c41e7c112147029cde1e3a310645f62020-12-20T12:10:36ZengSpringerOpenNanoscale Research Letters1931-75731556-276X2019-12-0114111010.1186/s11671-019-3169-6Heating Efficiency of Triple Vortex State Cylindrical Magnetic NanoparticlesDe Wei Wong0Wei Liang Gan1Yuan Kai Teo2Wen Siang Lew3School of Physical and Mathematical Sciences, Nanyang Technological UniversitySchool of Physical and Mathematical Sciences, Nanyang Technological UniversitySchool of Biological Sciences, Nanyang Technological UniversitySchool of Physical and Mathematical Sciences, Nanyang Technological UniversityAbstract A well-established method for treating cancerous tumors is magnetic hyperthermia, which uses localized heat generated by the relaxation mechanism of magnetic nanoparticles (MNPs) in a high-frequency alternating magnetic field. In this work, we investigate the heating efficiency of cylindrical NiFe MNPs, fabricated by template-assisted pulsed electrodeposition combined with differential chemical etching. The cylindrical geometry of the MNP enables the formation of the triple vortex state, which increases the heat generation efficiency by four times. Using time-dependent calorimetric measurements, the specific absorption rate (SAR) of the MNPs was determined and compared with the numerical calculations from micromagnetic simulations and vibrating sample magnetometer measurements. The magnetization reversal of high aspect ratios MNPs showed higher remanent magnetization and low-field susceptibility leading to higher hysteresis losses, which was reflected in higher experimental and theoretical SAR values. The SAR dependence on magnetic field strength exhibited small SAR values at low magnetic fields and saturates at high magnetic fields, which is correlated to the coercive field of the MNPs and a characteristic feature of ferromagnetic MNPs. The optimization of cylindrical NiFe MNPs will play a pivotal role in producing high heating performance and biocompatible magnetic hyperthermia agents.https://doi.org/10.1186/s11671-019-3169-6Magnetic nanoparticlesMagnetic hyperthermiaSpecific absorption rateHeLa cells
collection DOAJ
language English
format Article
sources DOAJ
author De Wei Wong
Wei Liang Gan
Yuan Kai Teo
Wen Siang Lew
spellingShingle De Wei Wong
Wei Liang Gan
Yuan Kai Teo
Wen Siang Lew
Heating Efficiency of Triple Vortex State Cylindrical Magnetic Nanoparticles
Nanoscale Research Letters
Magnetic nanoparticles
Magnetic hyperthermia
Specific absorption rate
HeLa cells
author_facet De Wei Wong
Wei Liang Gan
Yuan Kai Teo
Wen Siang Lew
author_sort De Wei Wong
title Heating Efficiency of Triple Vortex State Cylindrical Magnetic Nanoparticles
title_short Heating Efficiency of Triple Vortex State Cylindrical Magnetic Nanoparticles
title_full Heating Efficiency of Triple Vortex State Cylindrical Magnetic Nanoparticles
title_fullStr Heating Efficiency of Triple Vortex State Cylindrical Magnetic Nanoparticles
title_full_unstemmed Heating Efficiency of Triple Vortex State Cylindrical Magnetic Nanoparticles
title_sort heating efficiency of triple vortex state cylindrical magnetic nanoparticles
publisher SpringerOpen
series Nanoscale Research Letters
issn 1931-7573
1556-276X
publishDate 2019-12-01
description Abstract A well-established method for treating cancerous tumors is magnetic hyperthermia, which uses localized heat generated by the relaxation mechanism of magnetic nanoparticles (MNPs) in a high-frequency alternating magnetic field. In this work, we investigate the heating efficiency of cylindrical NiFe MNPs, fabricated by template-assisted pulsed electrodeposition combined with differential chemical etching. The cylindrical geometry of the MNP enables the formation of the triple vortex state, which increases the heat generation efficiency by four times. Using time-dependent calorimetric measurements, the specific absorption rate (SAR) of the MNPs was determined and compared with the numerical calculations from micromagnetic simulations and vibrating sample magnetometer measurements. The magnetization reversal of high aspect ratios MNPs showed higher remanent magnetization and low-field susceptibility leading to higher hysteresis losses, which was reflected in higher experimental and theoretical SAR values. The SAR dependence on magnetic field strength exhibited small SAR values at low magnetic fields and saturates at high magnetic fields, which is correlated to the coercive field of the MNPs and a characteristic feature of ferromagnetic MNPs. The optimization of cylindrical NiFe MNPs will play a pivotal role in producing high heating performance and biocompatible magnetic hyperthermia agents.
topic Magnetic nanoparticles
Magnetic hyperthermia
Specific absorption rate
HeLa cells
url https://doi.org/10.1186/s11671-019-3169-6
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AT weilianggan heatingefficiencyoftriplevortexstatecylindricalmagneticnanoparticles
AT yuankaiteo heatingefficiencyoftriplevortexstatecylindricalmagneticnanoparticles
AT wensianglew heatingefficiencyoftriplevortexstatecylindricalmagneticnanoparticles
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