An Unusual Presentation of T-Cell Lymphoblastic Lymphoma with Isolated Renal Involvement
The clinical presentation of Non-Hodgkin lymphoma (NHL) is frequently associated with the involvement of the abdomen and mediastinal lymphadenopathies, but rarely the kidney, ovaries, and testicles. Here, we report a rare case of T-cell lymphoblastic lymphoma (T-LBL) presenting with bilateral nephro...
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2019-01-01
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doaj-45b8a3fda74d4cee86e212e905bc9bfd2020-11-24T21:38:56ZengHindawi LimitedCase Reports in Hematology2090-65602090-65792019-01-01201910.1155/2019/28021412802141An Unusual Presentation of T-Cell Lymphoblastic Lymphoma with Isolated Renal InvolvementSultan Aydın Köker0Alper Koker1Adem Yasin Köksoy2Yasemin Kayadibi3Ülkü Gül Şiraz4Emine Tekin5Department of Pediatric Hematology and Oncology, SBÜ Van Education and Research Hospital, Van, TurkeyDepartment of Pediatric Intensive Care, Hatay State Hospital, Antakya, Hatay, TurkeyDepartment of Pediatrics, SBÜ Van Education and Research Hospital, Van, TurkeyDepartment of Radiology, SBÜ Van Education and Research Hospital, Van, TurkeyDepartment of Pediatrics, SBÜ Van Education and Research Hospital, Van, TurkeyDepartment of Pediatrics, SBÜ Van Education and Research Hospital, Van, TurkeyThe clinical presentation of Non-Hodgkin lymphoma (NHL) is frequently associated with the involvement of the abdomen and mediastinal lymphadenopathies, but rarely the kidney, ovaries, and testicles. Here, we report a rare case of T-cell lymphoblastic lymphoma (T-LBL) presenting with bilateral nephromegaly without acute renal failure (ARF) as the first manifestation. A 30-month-old boy was admitted to the department of pediatric nephrology exhibiting abdominal distension. Physical examination revealed bilateral renal palpation up to the inguinal region. Elevated lactate dehydrogenase (LDH) levels were detected in his blood. Bilateral diffuse enlarged kidneys with increased hypoechogenicity were found on abdominal ultrasonography. In the next step, contrast-enhanced computed tomography showed diffusely enlarged kidneys, which were compressing the intestinal bowels and midline structures. Renal biopsy demonstrated precursor T-LBL. We wish to report our patient with renal T-LBL presenting with diffuse renal enlargement, which has rarely been reported in the literature.http://dx.doi.org/10.1155/2019/2802141 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Sultan Aydın Köker Alper Koker Adem Yasin Köksoy Yasemin Kayadibi Ülkü Gül Şiraz Emine Tekin |
spellingShingle |
Sultan Aydın Köker Alper Koker Adem Yasin Köksoy Yasemin Kayadibi Ülkü Gül Şiraz Emine Tekin An Unusual Presentation of T-Cell Lymphoblastic Lymphoma with Isolated Renal Involvement Case Reports in Hematology |
author_facet |
Sultan Aydın Köker Alper Koker Adem Yasin Köksoy Yasemin Kayadibi Ülkü Gül Şiraz Emine Tekin |
author_sort |
Sultan Aydın Köker |
title |
An Unusual Presentation of T-Cell Lymphoblastic Lymphoma with Isolated Renal Involvement |
title_short |
An Unusual Presentation of T-Cell Lymphoblastic Lymphoma with Isolated Renal Involvement |
title_full |
An Unusual Presentation of T-Cell Lymphoblastic Lymphoma with Isolated Renal Involvement |
title_fullStr |
An Unusual Presentation of T-Cell Lymphoblastic Lymphoma with Isolated Renal Involvement |
title_full_unstemmed |
An Unusual Presentation of T-Cell Lymphoblastic Lymphoma with Isolated Renal Involvement |
title_sort |
unusual presentation of t-cell lymphoblastic lymphoma with isolated renal involvement |
publisher |
Hindawi Limited |
series |
Case Reports in Hematology |
issn |
2090-6560 2090-6579 |
publishDate |
2019-01-01 |
description |
The clinical presentation of Non-Hodgkin lymphoma (NHL) is frequently associated with the involvement of the abdomen and mediastinal lymphadenopathies, but rarely the kidney, ovaries, and testicles. Here, we report a rare case of T-cell lymphoblastic lymphoma (T-LBL) presenting with bilateral nephromegaly without acute renal failure (ARF) as the first manifestation. A 30-month-old boy was admitted to the department of pediatric nephrology exhibiting abdominal distension. Physical examination revealed bilateral renal palpation up to the inguinal region. Elevated lactate dehydrogenase (LDH) levels were detected in his blood. Bilateral diffuse enlarged kidneys with increased hypoechogenicity were found on abdominal ultrasonography. In the next step, contrast-enhanced computed tomography showed diffusely enlarged kidneys, which were compressing the intestinal bowels and midline structures. Renal biopsy demonstrated precursor T-LBL. We wish to report our patient with renal T-LBL presenting with diffuse renal enlargement, which has rarely been reported in the literature. |
url |
http://dx.doi.org/10.1155/2019/2802141 |
work_keys_str_mv |
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