An Unusual Presentation of T-Cell Lymphoblastic Lymphoma with Isolated Renal Involvement

The clinical presentation of Non-Hodgkin lymphoma (NHL) is frequently associated with the involvement of the abdomen and mediastinal lymphadenopathies, but rarely the kidney, ovaries, and testicles. Here, we report a rare case of T-cell lymphoblastic lymphoma (T-LBL) presenting with bilateral nephro...

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Main Authors: Sultan Aydın Köker, Alper Koker, Adem Yasin Köksoy, Yasemin Kayadibi, Ülkü Gül Şiraz, Emine Tekin
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2019/2802141
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spelling doaj-45b8a3fda74d4cee86e212e905bc9bfd2020-11-24T21:38:56ZengHindawi LimitedCase Reports in Hematology2090-65602090-65792019-01-01201910.1155/2019/28021412802141An Unusual Presentation of T-Cell Lymphoblastic Lymphoma with Isolated Renal InvolvementSultan Aydın Köker0Alper Koker1Adem Yasin Köksoy2Yasemin Kayadibi3Ülkü Gül Şiraz4Emine Tekin5Department of Pediatric Hematology and Oncology, SBÜ Van Education and Research Hospital, Van, TurkeyDepartment of Pediatric Intensive Care, Hatay State Hospital, Antakya, Hatay, TurkeyDepartment of Pediatrics, SBÜ Van Education and Research Hospital, Van, TurkeyDepartment of Radiology, SBÜ Van Education and Research Hospital, Van, TurkeyDepartment of Pediatrics, SBÜ Van Education and Research Hospital, Van, TurkeyDepartment of Pediatrics, SBÜ Van Education and Research Hospital, Van, TurkeyThe clinical presentation of Non-Hodgkin lymphoma (NHL) is frequently associated with the involvement of the abdomen and mediastinal lymphadenopathies, but rarely the kidney, ovaries, and testicles. Here, we report a rare case of T-cell lymphoblastic lymphoma (T-LBL) presenting with bilateral nephromegaly without acute renal failure (ARF) as the first manifestation. A 30-month-old boy was admitted to the department of pediatric nephrology exhibiting abdominal distension. Physical examination revealed bilateral renal palpation up to the inguinal region. Elevated lactate dehydrogenase (LDH) levels were detected in his blood. Bilateral diffuse enlarged kidneys with increased hypoechogenicity were found on abdominal ultrasonography. In the next step, contrast-enhanced computed tomography showed diffusely enlarged kidneys, which were compressing the intestinal bowels and midline structures. Renal biopsy demonstrated precursor T-LBL. We wish to report our patient with renal T-LBL presenting with diffuse renal enlargement, which has rarely been reported in the literature.http://dx.doi.org/10.1155/2019/2802141
collection DOAJ
language English
format Article
sources DOAJ
author Sultan Aydın Köker
Alper Koker
Adem Yasin Köksoy
Yasemin Kayadibi
Ülkü Gül Şiraz
Emine Tekin
spellingShingle Sultan Aydın Köker
Alper Koker
Adem Yasin Köksoy
Yasemin Kayadibi
Ülkü Gül Şiraz
Emine Tekin
An Unusual Presentation of T-Cell Lymphoblastic Lymphoma with Isolated Renal Involvement
Case Reports in Hematology
author_facet Sultan Aydın Köker
Alper Koker
Adem Yasin Köksoy
Yasemin Kayadibi
Ülkü Gül Şiraz
Emine Tekin
author_sort Sultan Aydın Köker
title An Unusual Presentation of T-Cell Lymphoblastic Lymphoma with Isolated Renal Involvement
title_short An Unusual Presentation of T-Cell Lymphoblastic Lymphoma with Isolated Renal Involvement
title_full An Unusual Presentation of T-Cell Lymphoblastic Lymphoma with Isolated Renal Involvement
title_fullStr An Unusual Presentation of T-Cell Lymphoblastic Lymphoma with Isolated Renal Involvement
title_full_unstemmed An Unusual Presentation of T-Cell Lymphoblastic Lymphoma with Isolated Renal Involvement
title_sort unusual presentation of t-cell lymphoblastic lymphoma with isolated renal involvement
publisher Hindawi Limited
series Case Reports in Hematology
issn 2090-6560
2090-6579
publishDate 2019-01-01
description The clinical presentation of Non-Hodgkin lymphoma (NHL) is frequently associated with the involvement of the abdomen and mediastinal lymphadenopathies, but rarely the kidney, ovaries, and testicles. Here, we report a rare case of T-cell lymphoblastic lymphoma (T-LBL) presenting with bilateral nephromegaly without acute renal failure (ARF) as the first manifestation. A 30-month-old boy was admitted to the department of pediatric nephrology exhibiting abdominal distension. Physical examination revealed bilateral renal palpation up to the inguinal region. Elevated lactate dehydrogenase (LDH) levels were detected in his blood. Bilateral diffuse enlarged kidneys with increased hypoechogenicity were found on abdominal ultrasonography. In the next step, contrast-enhanced computed tomography showed diffusely enlarged kidneys, which were compressing the intestinal bowels and midline structures. Renal biopsy demonstrated precursor T-LBL. We wish to report our patient with renal T-LBL presenting with diffuse renal enlargement, which has rarely been reported in the literature.
url http://dx.doi.org/10.1155/2019/2802141
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