DNA Topology and Global Architecture of Point Centromeres

DNA Topology and Global Architecture of Point Centromeres

DNA is wrapped in a left-handed fashion around histone octasomes containing the centromeric histone H3 variant CENP-A. However, DNA topology studies have suggested that DNA is wrapped in a right-handed manner around the CENP-A nucleosome that occupies the yeast point centromere. Here, we determine t...

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Bibliographic Details
Main Authors: Ofelia Díaz-Ingelmo, Belén Martínez-García, Joana Segura, Antonio Valdés, Joaquim Roca
Format: Article
Language:English
Published: Elsevier 2015-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715010505

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