Rapid epigenetic adaptation to uncontrolled heterochromatin spreading

Heterochromatin, a highly compact chromatin state characterized by histone H3K9 methylation and HP1 protein binding, silences the underlying DNA and influences the expression of neighboring genes. However, the mechanisms that regulate heterochromatin spreading are not well understood. In this study,...

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Bibliographic Details
Main Authors: Jiyong Wang, Bharat D Reddy, Songtao Jia
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-03-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/06179