Identification of nine genomic regions of amplification in urothelial carcinoma, correlation with stage, and potential prognostic and therapeutic value.

Identification of nine genomic regions of amplification in urothelial carcinoma, correlation with stage, and potential prognostic and therapeutic value.

We performed a genome wide analysis of 164 urothelial carcinoma samples and 27 bladder cancer cell lines to identify copy number changes associated with disease characteristics, and examined the association of amplification events with stage and grade of disease. Multiplex inversion probe (MIP) anal...

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Bibliographic Details
Main Authors: Yvonne Chekaluk, Chin-Lee Wu, Jonathan Rosenberg, Markus Riester, Qishan Dai, Sharron Lin, Yanan Guo, W Scott McDougal, David J Kwiatkowski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3617176?pdf=render

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