Inducing maternal inflammation promotes leptin production in offspring but does not improve allergic symptoms in a mouse model of allergic rhinitis

Aims: The intrauterine environment is considered to affect immunological development in fetus, leading to an increased risk of developing allergy. In particular, maternal lipopolysaccharides (LPS) administration might regulate the development of allergic disease in offspring. Several studies have sh...

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Bibliographic Details
Main Authors: Atsuko Imai, Keiko Satoi, Eka Fujimoto, Kazuto Sato
Format: Article
Language:English
Published: Elsevier 2017-06-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844016323155