Hepcidin- A Burgeoning Biomarker

Hepcidin- A Burgeoning Biomarker

The discovery of hepcidin has triggered a virtual ignition of studies on iron metabolism and related disorders. The peptide hormone hepcidin is a key homeostatic regulator of iron metabolism. The synthesis of hepcidin is induced by systemic iron levels and by inflammatory stimuli. Several human dise...

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Bibliographic Details
Main Authors: Hemkant Manikrao Deshmukh, Rajesh Bhanudas Rajekar, Vinayak Wamanrao Patil, Vidya Sanjay Nagar
Format: Article
Language:English
Published: JCDR Research and Publications Pvt. Ltd. 2017-10-01
Series:National Journal of Laboratory Medicine
Subjects:
Anaemia
Ferritin
Ferroportin
Human Immunodeficiency Virus
Interleukin
Online Access:http://www.njlm.net/articles/PDF/2264/29251_CE[VSU]_F(AK)_PF1(VSU_GG)_PFA(VSU_GG)_PF2(VSU_GG).pdf
Description
Summary:The discovery of hepcidin has triggered a virtual ignition of studies on iron metabolism and related disorders. The peptide hormone hepcidin is a key homeostatic regulator of iron metabolism. The synthesis of hepcidin is induced by systemic iron levels and by inflammatory stimuli. Several human diseases are associated with variations in hepcidin concentrations. The evaluation of hepcidin in biological fluids is therefore a promising device in the diagnosis and management of medical situations in which iron metabolism is affected. Thus, it made us to recapitulate role of hepcidin as biomarker.
ISSN:2277-8551
2455-6882

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