Blood-Borne ST6GAL1 Regulates Immunoglobulin Production in B Cells

Humoral immunity is an effective but metabolically expensive defense mechanism. It is unclear whether systemic cues exist to communicate the dynamic need for antigen presentation and immunoglobulin production. Here, we report a novel role for the liver-produced, acute phase reactant ST6GAL1 in IgG p...

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Bibliographic Details
Main Authors: Eric E. Irons, Patrick R. Punch, Joseph T. Y. Lau
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Immunology
Subjects:
IgG
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00617/full