Quantitative Assessment and Prognostic Associations of the Immune Landscape in Ovarian Clear Cell Carcinoma

Quantitative Assessment and Prognostic Associations of the Immune Landscape in Ovarian Clear Cell Carcinoma

Ovarian clear cell carcinoma (OCCC) is a rare subtype of epithelial ovarian cancer characterised by a high frequency of loss-of-function <i>ARID1A</i> mutations and a poor response to chemotherapy. Despite their generally low mutational burden, an intratumoural T cell response has been r...

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Bibliographic Details
Main Authors: Saira Khalique, Sarah Nash, David Mansfield, Julian Wampfler, Ayoma Attygale, Katherine Vroobel, Harriet Kemp, Richard Buus, Hannah Cottom, Ioannis Roxanis, Thomas Jones, Katharina von Loga, Dipa Begum, Naomi Guppy, Pradeep Ramagiri, Kerry Fenwick, Nik Matthews, Michael J. F. Hubank, Christopher J. Lord, Syed Haider, Alan Melcher, Susana Banerjee, Rachael Natrajan
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cancers
Subjects:
immune microenvironment
ARID1A
clear cell ovarian cancer
next generation sequencing
biomarker
Online Access:https://www.mdpi.com/2072-6694/13/15/3854

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