Tracking the evolution of dengue virus strains D2S10 and D2S20 by 454 pyrosequencing.

Dengue virus is the most prevalent mosquito-borne virus worldwide. In this study, we used pyrosequencing to analyze the whole viral genome of two mouse-adapted strains, D2S10 and D2S20, that induce a dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS)-like lethal disease in mice lacking the typ...

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Bibliographic Details
Main Authors: Huda Makhluf, Michael D Buck, Kevin King, Stuart T Perry, Matthew R Henn, Sujan Shresta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3544829?pdf=render