CRIF1 interacting with CDK2 regulates bone marrow microenvironment-induced G0/G1 arrest of leukemia cells.

CRIF1 interacting with CDK2 regulates bone marrow microenvironment-induced G0/G1 arrest of leukemia cells.

BACKGROUND: To assess the level of CR6-interacting factor 1 (CRIF1), a cell cycle negative regulator, in patients with leukemia and investigate the role of CRIF1 in regulating leukemia cell cycle. METHODS: We compared the CRIF1 level in bone marrow (BM) samples from healthy and acute myeloid leukemi...

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Bibliographic Details
Main Authors:	Qian Ran, Ping Hao, Yanni Xiao, Lixing Xiang, Xingde Ye, Xiaojun Deng, Jiang Zhao, Zhongjun Li
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2014-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3919709?pdf=render

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