Bone morphogenetic protein signaling protects against cerulein-induced pancreatic fibrosis.

Bone morphogenetic proteins (BMPs) have an anti-fibrogenic function in the kidney, lung, and liver. However, their role in chronic pancreatitis (CP) is unknown. The aim of this study was to define the anti-fibrogenic role of BMP signaling in the pancreas in vivo under CP induction. Mice with a delet...

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Bibliographic Details
Main Authors: Xuxia Gao, Yanna Cao, Dustin A Staloch, Michael A Gonzales, Judith F Aronson, Celia Chao, Mark R Hellmich, Tien C Ko
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3931685?pdf=render