Effect of maternal and post weaning folate supply on gene-specific DNA methylation in the small intestine of weaning and adult Apc+/Min and wild type mice.

Increasing evidence supports the developmental origins of adult health and disease hypothesis which argues for a causal relationship between adverse early life nutrition and increased disease risk in adulthood. Modulation of epigenetic marks, e.g. DNA methylation and consequential altered gene expr...

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Bibliographic Details
Main Authors: Jill Ann Mckay, Elizabeth A Williams, John Cummings Mathers
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-05-01
Series:Frontiers in Genetics
Subjects:
CRC
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2011.00023/full