E and prM proteins of genotype V Japanese encephalitis virus are required for its increased virulence in mice
We previously showed that the Japanese encephalitis virus (JEV) genotype V (GV) strain Muar exhibits significantly higher virulence in mice than the genotype I (GI) JEV strain Mie/41/2002. In this study, we attempted to identify the region responsible for the increased virulence of GV JEV using reco...
Main Authors: | Shigeru Tajima, Ken-ichi Shibasaki, Satoshi Taniguchi, Eri Nakayama, Takahiro Maeki, Chang-Kweng Lim, Masayuki Saijo |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-11-01
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Series: | Heliyon |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844019365417 |
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