Impact of ischemia-reperfusion on extracellular matrix processing and structure of the basement membrane of the heart.

Impact of ischemia-reperfusion on extracellular matrix processing and structure of the basement membrane of the heart.

PURPOSE: Acute ischemic injury is a strong inductor of cardiac remodelling, resulting in structural changes of the extracellular matrix (ECM) and basement membrane (BM). In a large animal model of ischemia-reperfusion (I/R) we investigated the post-ischemic liberation of the collagen-IV-fragments Tu...

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Bibliographic Details
Main Authors: Alexander Lauten, Alexandra Gerhard-Garcia, Frank Suhr, Juergen H Fischer, Hans R Figulla, Wilhelm Bloch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3969375?pdf=render

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