Matrine Exerts a Strong Anti-Arthritic Effect on Type II Collagen-Induced Arthritis in Rats by Inhibiting Inflammatory Responses

Matrine Exerts a Strong Anti-Arthritic Effect on Type II Collagen-Induced Arthritis in Rats by Inhibiting Inflammatory Responses

To investigate anti-arthritic effects of matrine isolated from the roots of S. flavescens on type II collagen-induced arthritis (CIA) in rats and to explore its related potential mechanisms, CIA rats were established and administered with matrine (20, 40 or 80 mg/kg/days, for 30 days). Subsequently,...

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Bibliographic Details
Main Authors: Jiang Pu, Fan-Fu Fang, Xiu-Qing Li, Zhi-Heng Shu, Yi-Ping Jiang, Ting Han, Wei Peng, Cheng-Jian Zheng
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:International Journal of Molecular Sciences
Subjects:
matrine
Sophora flavescens
rheumatoid arthritis
anti-arthritic effect
type II collagen
Online Access:http://www.mdpi.com/1422-0067/17/9/1410

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