Three-dimensional sensitivity mapping of a handheld magnetic probe for sentinel lymph node biopsy

An experimental apparatus for three-dimensional sensitivity mapping of a handheld magnetic probe with a permanent magnet and a Hall sensor was developed. To optimize the shapes and sizes of the magnets, the sensitivity mappings of two types of magnets, column- and cone-type magnets, were evaluated b...

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Main Authors: Akihiro Kuwahata, Shinichi Chikaki, Aslı Ergin, Miki Kaneko, Moriaki Kusakabe, Masaki Sekino
Format: Article
Language:English
Published: AIP Publishing LLC 2017-05-01
Series:AIP Advances
Online Access:http://dx.doi.org/10.1063/1.4976338
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spelling doaj-453a6e03e96440a1a14bebf6e8ad18bd2020-11-25T01:01:09ZengAIP Publishing LLCAIP Advances2158-32262017-05-0175056720056720-510.1063/1.4976338229791ADVThree-dimensional sensitivity mapping of a handheld magnetic probe for sentinel lymph node biopsyAkihiro Kuwahata0Shinichi Chikaki1Aslı Ergin2Miki Kaneko3Moriaki Kusakabe4Masaki Sekino5Graduate School of Engineering, The University of Tokyo, Tokyo, 113-8656, JapanGraduate School of Engineering, The University of Tokyo, Tokyo, 113-8656, JapanGraduate School of Engineering, The University of Tokyo, Tokyo, 113-8656, JapanGraduate School of Engineering, The University of Tokyo, Tokyo, 113-8656, JapanGraduate School of Agricultural and Life Sciences, The University of Tokyo, 113-8656, JapanGraduate School of Engineering, The University of Tokyo, Tokyo, 113-8656, JapanAn experimental apparatus for three-dimensional sensitivity mapping of a handheld magnetic probe with a permanent magnet and a Hall sensor was developed. To optimize the shapes and sizes of the magnets, the sensitivity mappings of two types of magnets, column- and cone-type magnets, were evaluated by the experimental apparatus. The longitudinal sensitivities of column and cone types are 8 and 9 mm, respectively, for 5 μL of magnetic nanoparticles. The measured longitudinal sensitivities agree well with the sensitivities calculated by the finite element method. Furthermore, the maximum lateral resolutions of column and cone types are 4.1 and 3.7 mm, respectively. In terms of the directionality, the sensitivities of column and cone types of the angle of 90° with respect to the probe axis fall approximately to 72% and 50% at 6 mm distance from the probe head, indicating that the cone type has high directionality due to its sharp shape. The measurement of sensitivity mapping revealed that the characteristics of the cone-type magnet are superior to that of the column-type magnet for the identification of sentinel lymph nodes.http://dx.doi.org/10.1063/1.4976338
collection DOAJ
language English
format Article
sources DOAJ
author Akihiro Kuwahata
Shinichi Chikaki
Aslı Ergin
Miki Kaneko
Moriaki Kusakabe
Masaki Sekino
spellingShingle Akihiro Kuwahata
Shinichi Chikaki
Aslı Ergin
Miki Kaneko
Moriaki Kusakabe
Masaki Sekino
Three-dimensional sensitivity mapping of a handheld magnetic probe for sentinel lymph node biopsy
AIP Advances
author_facet Akihiro Kuwahata
Shinichi Chikaki
Aslı Ergin
Miki Kaneko
Moriaki Kusakabe
Masaki Sekino
author_sort Akihiro Kuwahata
title Three-dimensional sensitivity mapping of a handheld magnetic probe for sentinel lymph node biopsy
title_short Three-dimensional sensitivity mapping of a handheld magnetic probe for sentinel lymph node biopsy
title_full Three-dimensional sensitivity mapping of a handheld magnetic probe for sentinel lymph node biopsy
title_fullStr Three-dimensional sensitivity mapping of a handheld magnetic probe for sentinel lymph node biopsy
title_full_unstemmed Three-dimensional sensitivity mapping of a handheld magnetic probe for sentinel lymph node biopsy
title_sort three-dimensional sensitivity mapping of a handheld magnetic probe for sentinel lymph node biopsy
publisher AIP Publishing LLC
series AIP Advances
issn 2158-3226
publishDate 2017-05-01
description An experimental apparatus for three-dimensional sensitivity mapping of a handheld magnetic probe with a permanent magnet and a Hall sensor was developed. To optimize the shapes and sizes of the magnets, the sensitivity mappings of two types of magnets, column- and cone-type magnets, were evaluated by the experimental apparatus. The longitudinal sensitivities of column and cone types are 8 and 9 mm, respectively, for 5 μL of magnetic nanoparticles. The measured longitudinal sensitivities agree well with the sensitivities calculated by the finite element method. Furthermore, the maximum lateral resolutions of column and cone types are 4.1 and 3.7 mm, respectively. In terms of the directionality, the sensitivities of column and cone types of the angle of 90° with respect to the probe axis fall approximately to 72% and 50% at 6 mm distance from the probe head, indicating that the cone type has high directionality due to its sharp shape. The measurement of sensitivity mapping revealed that the characteristics of the cone-type magnet are superior to that of the column-type magnet for the identification of sentinel lymph nodes.
url http://dx.doi.org/10.1063/1.4976338
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