An approach to control relapse of inflammatory lesions after discontinuation of primary therapy.

Long-term treatment with the fungal metabolite drug FTY720 (Fingolimod) was shown to be highly effective in controlling viral immunopathological lesions. However, in this report we show that the anti-inflammatory effect of FTY720 in herpes simplex virus-1 (HSV-1) induced ocular inflammation is lost...

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Bibliographic Details
Main Authors: Pradeep B J Reddy, Sharvan Sehrawat, Amol Suryawanshi, Naveen K Rajasagi, Madhu Khatri, Barry T Rouse
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4028216?pdf=render