Recyclable and Stable <i>α</i>-Methylproline-Derived Chiral Ligands for the Chemical Dynamic Kinetic Resolution of free <i>C,N</i>-Unprotected <i>α</i>-Amino Acids

Recyclable and Stable <i>α</i>-Methylproline-Derived Chiral Ligands for the Chemical Dynamic Kinetic Resolution of free <i>C,N</i>-Unprotected <i>α</i>-Amino Acids

A novel special designed, stable, and recyclable chiral ligand bearing a quaternary carbon was developed for chemical dynamic kinetic resolution (DKR) of free <i>C,N</i>-unprotected racemic &#945;-amino acids via Schiff base intermediates. This method furnishes high yields with excel...

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Bibliographic Details
Main Authors: Shuangjie Shu, Liang Zhao, Shengbin Zhou, Chenglin Wu, Hong Liu, Jiang Wang
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Molecules
Subjects:
quaternary carbon
dynamic kinetic resolution
unprotected <i>α</i>-amino acids
Schiff base intermediates
ligands
Online Access:https://www.mdpi.com/1420-3049/24/12/2218

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