Identification of microRNAs and their Endonucleolytic Cleavaged target mRNAs in colorectal cancer

Identification of microRNAs and their Endonucleolytic Cleavaged target mRNAs in colorectal cancer

Abstract Background Colorectal cancer (CRC) ranks the third among the most common malignancies globally. It is well known that microRNAs (miRNAs) play vital roles in destabilizing mRNAs and repressing their translations in this disease. However, the mechanism of miRNA-induced mRNA cleavage remains t...

Full description

Bibliographic Details
Main Authors:	Fangbin Zhou, Donge Tang, Yong Xu, Huiyan He, Yan Wu, Liewen Lin, Jun Dong, Wenyong Tan, Yong Dai
Format:	Article
Language:	English
Published:	BMC 2020-03-01
Series:	BMC Cancer
Subjects:	microRNA Colorectal Cancer High-throughput small RNA sequencing Degradome sequencing Endonucleolytic cleavage
Online Access:	http://link.springer.com/article/10.1186/s12885-020-06717-4

Similar Items

High-throughput deep sequencing reveals the important role that microRNAs play in the salt response in sweet potato (Ipomoea batatas L.)
by: Zhengmei Yang, et al.
Published: (2020-02-01)

Analysis of microRNAs, phased small interfering RNAs and their potential targets in Rosa rugosa Thunb.
by: Junqiang Guo, et al.
Published: (2019-04-01)

Identification and integrated analysis of glyphosate stress-responsive microRNAs, lncRNAs, and mRNAs in rice using genome-wide high-throughput sequencing
by: Rongrong Zhai, et al.
Published: (2020-03-01)

Identification of miRNAs and Their Targets in Cotton Inoculated with Verticillium dahliae by High-Throughput Sequencing and Degradome Analysis
by: Yujuan Zhang, et al.
Published: (2015-06-01)

Identification and Functional Analysis of MicroRNAs and Their Targets in Platanus acerifolia under Lead (Pb) Stress
by: Yuanlong Wang, et al.
Published: (2015-03-01)

Integration of Transcriptomes, Small RNAs, and Degradome Sequencing to Identify Putative miRNAs and Their Targets Related to Eu-Rubber Biosynthesis in <i>Eucommia ulmoides</i>
by: Jing Ye, et al.
Published: (2019-08-01)

Identification of microRNAs Involved in Regeneration of the Secondary Vascular System in Populus tomentosa Carr.
by: Fang eTang, et al.
Published: (2016-05-01)

An improved method of constructing degradome library suitable for sequencing using Illumina platform
by: Yong-Fang Li, et al.
Published: (2019-11-01)

Genome-Wide Investigation of MicroRNAs and Their Targets in Response to Freezing Stress in Medicago sativa L., Based on High-Throughput Sequencing
by: Yongjun Shu, et al.
Published: (2016-03-01)

Integration Analysis of Small RNA and Degradome Sequencing Reveals MicroRNAs Responsive to Dickeya zeae in Resistant Rice
by: Wenqi Li, et al.
Published: (2019-01-01)

Exploration of microRNAs and their targets engaging in the resistance interaction between wheat and stripe rust
by: Hao eFeng, et al.
Published: (2015-06-01)

Transcriptome-Wide Analysis of Botrytis elliptica Responsive microRNAs and Their Targets in Lilium Regale Wilson by High-Throughput Sequencing and Degradome Analysis
by: Xue Gao, et al.
Published: (2017-05-01)

Identification of Salt Tolerance-related microRNAs and Their Targets in Maize (Zea mays L.) Using High-throughput Sequencing and Degradome Analysis
by: Rong Fu, et al.
Published: (2017-05-01)

Feature selection for RNA cleavage efficiency at specific sites using the LASSO regression model in Arabidopsis thaliana
by: Daishin Ueno, et al.
Published: (2021-07-01)

Pathological Grade-Associated Transcriptome Profiling of lncRNAs and mRNAs in Gliomas
by: Junlong Sun, et al.
Published: (2020-03-01)

Small RNA and Degradome Deep Sequencing Reveals the Roles of microRNAs in Seed Expansion in Peanut (Arachis hypogaea L.)
by: Xingli Ma, et al.
Published: (2018-03-01)

snR30/U17 Small Nucleolar Ribonucleoprotein: A Critical Player during Ribosome Biogenesis
by: Timothy John Vos, et al.
Published: (2020-09-01)

PmiRDiscVali: an integrated pipeline for plant microRNA discovery and validation
by: Dongliang Yu, et al.
Published: (2019-02-01)

Identification of miRNAs and their targets using high-throughput sequencing and degradome analysis in cytoplasmic male-sterile and its maintainer fertile lines of <it>brassica juncea</it>
by: Yang Jinghua, et al.
Published: (2013-01-01)

MicroRNAs Involved in Regulatory Cytoplasmic Male Sterility by Analysis RNA-seq and Small RNA-seq in Soybean
by: Chunbao Zhang, et al.
Published: (2021-05-01)

Comparative Analysis of Fruit Ripening-Related miRNAs and Their Targets in Blueberry Using Small RNA and Degradome Sequencing
by: Yanming Hou, et al.
Published: (2017-12-01)

High-throughput sequencing reveals microRNAs and their targets in response to drought stress in wheat (Triticum aestivum L.)
by: Ye Hua, et al.
Published: (2019-01-01)

Comparative analysis of miRNAs and their target transcripts between a spontaneous late-ripening sweet orange mutant and its wild-type using small RNA and degradome sequencing
by: Juxun Wu, et al.
Published: (2016-09-01)

Water-deficit responsive microRNAs in the primary root growth zone of maize
by: Candace M. Seeve, et al.
Published: (2019-10-01)

Genome-wide identification of alternate bearing-associated microRNAs (miRNAs) in olive (<it>Olea europaea</it> L.)
by: Yanik Huriye, et al.
Published: (2013-01-01)

Identification and characterisation of microRNAs and their target genes in phosphate-starved Nicotiana benthamiana by small RNA deep sequencing and 5’RACE analysis
by: Amanda Huen, et al.
Published: (2018-12-01)

Identification and Function Prediction of Novel MicroRNAs in Laoshan Dairy Goats
by: Zhibin Ji, et al.
Published: (2013-03-01)

Genome-Wide Profiling of Small RNAs and Degradome Revealed Conserved Regulations of miRNAs on Auxin-Responsive Genes during Fruit Enlargement in Peaches
by: Mengya Shi, et al.
Published: (2017-12-01)

Transcriptome analysis reveals new microRNAs-mediated pathway involved in anther development in male sterile wheat
by: Longqing Sun, et al.
Published: (2018-05-01)

High-Throughput microRNA and mRNA Sequencing Reveals that microRNAs May Be Involved in Melatonin-Mediated Cold Tolerance in Citrullus Lanatus L.
by: Hao Li, et al.
Published: (2016-08-01)

Genome-wide identification and comprehensive analysis of microRNAs and phased small interfering RNAs in watermelon
by: Li Liu, et al.
Published: (2018-05-01)

High-throughput sequencing identification of differentially expressed microRNAs in metastatic ovarian cancer with experimental validations
by: Yang Gu, et al.
Published: (2020-10-01)

Transcriptomic analysis of long noncoding RNAs and mRNAs expression profiles in the spinal cord of bone cancer pain rats
by: Xinran Hou, et al.
Published: (2020-03-01)

Identification of Regulatory Networks of MicroRNAs and Their Targets in Response to Colletotrichum gloeosporioides in Tea Plant (Camellia sinensis L.)
by: Anburaj Jeyaraj, et al.
Published: (2019-09-01)

microRNAs and Their Targets in Apple (Malus domestica cv. “Fuji”) Involved in Response to Infection of Pathogen Valsa mali
by: Hao Feng, et al.
Published: (2017-12-01)

Uncovering anthocyanin biosynthesis related microRNAs and their target genes by small RNA and degradome sequencing in tuberous roots of sweetpotato
by: Liheng He, et al.
Published: (2019-06-01)

MicroRNAs as Biomarkers in Colorectal Cancer
by: Takaaki Masuda, et al.
Published: (2017-09-01)

Identification and expression profiling of microRNAs involved in the stigma exsertion under high-temperature stress in tomato
by: Changtian Pan, et al.
Published: (2017-11-01)

Genome-wide identification of microRNAs and their targets in wild type and phyB mutant provides a key link between microRNAs and the phyB-mediated light signaling pathway in rice
by: Xian-Zhi eXie, et al.
Published: (2015-05-01)

Integrated small RNA and mRNA expression profiles reveal miRNAs and their target genes in response to Aspergillus flavus growth in peanut seeds
by: Chuanzhi Zhao, et al.
Published: (2020-05-01)