Tissue-specific (ts)CRISPR as an efficient strategy for in vivo screening in Drosophila
Applicability of CRISPR-Cas9 for in vivo screening has so far been limited. Here the authors characterize tissue specific CRISPR in the Drosophila mushroom body, generating a library of gRNA-harboring plasmids and fly lines for in vivo screening.
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2019-05-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-019-10140-0 |