Buoyancy-Free Janus Microcylinders as Mobile Microelectrode Arrays for Continuous Microfluidic Biomolecule Collection within a Wide Frequency Range: A Numerical Simulation Study
We numerically study herein the AC electrokinetic motion of Janus mobile microelectrode (ME) arrays in electrolyte solution in a wide field frequency, which holds great potential for biomedical applications. A fully coupled physical model, which incorporates the fluid-structure interaction under the...
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doaj-45254855bb654d4db968be9dcd3cc6fc2020-11-25T02:57:38ZengMDPI AGMicromachines2072-666X2020-03-0111328910.3390/mi11030289mi11030289Buoyancy-Free Janus Microcylinders as Mobile Microelectrode Arrays for Continuous Microfluidic Biomolecule Collection within a Wide Frequency Range: A Numerical Simulation StudyWeiyu Liu0Yukun Ren1Ye Tao2Hui Yan3Congda Xiao4Qisheng Wu5School of Electronics and Control Engineering, Chang’an University, Middle-Section of Nan’er Huan Road, Xi’an 710064, ChinaState Key Laboratory of Robotics and System, Harbin Institute of Technology, West Da-zhi Street 92, Harbin 150001, ChinaState Key Laboratory of Robotics and System, Harbin Institute of Technology, West Da-zhi Street 92, Harbin 150001, ChinaSchool of Mechatronics Engineering, Harbin Institute of Technology, West Da-zhi Street 92, Harbin 150001, ChinaSchool of Electronics and Control Engineering, Chang’an University, Middle-Section of Nan’er Huan Road, Xi’an 710064, ChinaSchool of Electronics and Control Engineering, Chang’an University, Middle-Section of Nan’er Huan Road, Xi’an 710064, ChinaWe numerically study herein the AC electrokinetic motion of Janus mobile microelectrode (ME) arrays in electrolyte solution in a wide field frequency, which holds great potential for biomedical applications. A fully coupled physical model, which incorporates the fluid-structure interaction under the synergy of induced-charge electroosmotic (ICEO) slipping and interfacial Maxwell stress, is developed for this purpose. A freely suspended Janus cylinder free from buoyancy, whose main body is made of polystyrene, while half of the particle surface is coated with a thin conducting film of negligible thickness, will react actively on application of an AC signal. In the low-frequency limit, induced-charge electrophoretic (ICEP) translation occurs due to symmetric breaking in ICEO slipping, which renders the insulating end to move ahead. At higher field frequencies, a brand-new electrokinetic transport phenomenon called “ego-dielectrophoresis (e-DEP)” arises due to the action of the localized uneven field on the inhomogeneous particle dipole moment. In stark contrast with the low-frequency ICEP translation, the high-frequency e-DEP force tends to drive the asymmetric dipole moment to move in the direction of the conducting end. The bidirectional transport feature of Janus microspheres in a wide AC frequency range can be vividly interpreted as an array of ME for continuous loading of secondary bioparticles from the surrounding liquid medium along its direction-controllable path by long-range electroconvection. These results pave the way for achieving flexible and high-throughput on-chip extraction of nanoscale biological contents for subsequent on-site bioassay based upon AC electrokinetics of Janus ME arrays.https://www.mdpi.com/2072-666X/11/3/289induced-charge electrokinetic phenomenonego-dielectrophoresismobile electrodejanus microspherecontinuous biomolecule collectionelectroconvection |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Weiyu Liu Yukun Ren Ye Tao Hui Yan Congda Xiao Qisheng Wu |
spellingShingle |
Weiyu Liu Yukun Ren Ye Tao Hui Yan Congda Xiao Qisheng Wu Buoyancy-Free Janus Microcylinders as Mobile Microelectrode Arrays for Continuous Microfluidic Biomolecule Collection within a Wide Frequency Range: A Numerical Simulation Study Micromachines induced-charge electrokinetic phenomenon ego-dielectrophoresis mobile electrode janus microsphere continuous biomolecule collection electroconvection |
author_facet |
Weiyu Liu Yukun Ren Ye Tao Hui Yan Congda Xiao Qisheng Wu |
author_sort |
Weiyu Liu |
title |
Buoyancy-Free Janus Microcylinders as Mobile Microelectrode Arrays for Continuous Microfluidic Biomolecule Collection within a Wide Frequency Range: A Numerical Simulation Study |
title_short |
Buoyancy-Free Janus Microcylinders as Mobile Microelectrode Arrays for Continuous Microfluidic Biomolecule Collection within a Wide Frequency Range: A Numerical Simulation Study |
title_full |
Buoyancy-Free Janus Microcylinders as Mobile Microelectrode Arrays for Continuous Microfluidic Biomolecule Collection within a Wide Frequency Range: A Numerical Simulation Study |
title_fullStr |
Buoyancy-Free Janus Microcylinders as Mobile Microelectrode Arrays for Continuous Microfluidic Biomolecule Collection within a Wide Frequency Range: A Numerical Simulation Study |
title_full_unstemmed |
Buoyancy-Free Janus Microcylinders as Mobile Microelectrode Arrays for Continuous Microfluidic Biomolecule Collection within a Wide Frequency Range: A Numerical Simulation Study |
title_sort |
buoyancy-free janus microcylinders as mobile microelectrode arrays for continuous microfluidic biomolecule collection within a wide frequency range: a numerical simulation study |
publisher |
MDPI AG |
series |
Micromachines |
issn |
2072-666X |
publishDate |
2020-03-01 |
description |
We numerically study herein the AC electrokinetic motion of Janus mobile microelectrode (ME) arrays in electrolyte solution in a wide field frequency, which holds great potential for biomedical applications. A fully coupled physical model, which incorporates the fluid-structure interaction under the synergy of induced-charge electroosmotic (ICEO) slipping and interfacial Maxwell stress, is developed for this purpose. A freely suspended Janus cylinder free from buoyancy, whose main body is made of polystyrene, while half of the particle surface is coated with a thin conducting film of negligible thickness, will react actively on application of an AC signal. In the low-frequency limit, induced-charge electrophoretic (ICEP) translation occurs due to symmetric breaking in ICEO slipping, which renders the insulating end to move ahead. At higher field frequencies, a brand-new electrokinetic transport phenomenon called “ego-dielectrophoresis (e-DEP)” arises due to the action of the localized uneven field on the inhomogeneous particle dipole moment. In stark contrast with the low-frequency ICEP translation, the high-frequency e-DEP force tends to drive the asymmetric dipole moment to move in the direction of the conducting end. The bidirectional transport feature of Janus microspheres in a wide AC frequency range can be vividly interpreted as an array of ME for continuous loading of secondary bioparticles from the surrounding liquid medium along its direction-controllable path by long-range electroconvection. These results pave the way for achieving flexible and high-throughput on-chip extraction of nanoscale biological contents for subsequent on-site bioassay based upon AC electrokinetics of Janus ME arrays. |
topic |
induced-charge electrokinetic phenomenon ego-dielectrophoresis mobile electrode janus microsphere continuous biomolecule collection electroconvection |
url |
https://www.mdpi.com/2072-666X/11/3/289 |
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