Lower Ventromedial Prefrontal Cortex Glutamate Levels in Patients With Obsessive–Compulsive Disorder

Lower Ventromedial Prefrontal Cortex Glutamate Levels in Patients With Obsessive–Compulsive Disorder

Background: Recent studies using magnetic resonance spectroscopy (1H-MRS) indicate that patients with obsessive–compulsive disorder (OCD) present abnormal levels of glutamate (Glu) and gamma aminobutyric acid (GABA) in the frontal and striatal regions of the brain. These abnormalities could be relat...

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Bibliographic Details
Main Authors: Marcelo C. Batistuzzo, Bruna A. Sottili, Roseli G. Shavitt, Antonio C. Lopes, Carolina Cappi, Maria Alice de Mathis, Bruno Pastorello, Juliana B. Diniz, Renata M. F. Silva, Euripedes C. Miguel, Marcelo Q. Hoexter, Maria C. Otaduy
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Psychiatry
Subjects:
obsessive-compulsive disorder
magnetic resonance spectroscopy
prefrontal cortex
neurometabolic alterations
Glutamate
GABA
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2021.668304/full

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