Hepatocyte-specific expression of constitutively active Alk5 exacerbates thioacetamide-induced liver injury in mice
While Transforming growth factor-βs (Tgf-βs) have been known to play an important role in liver fibrosis through an activation of Hepatic Stellate Cells (HSC), their fibrotic role on hepatocytes in liver damage has not been addressed thoroughly. To shed more light on the hepatocyte-specific role of...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2017-05-01
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Series: | Heliyon |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844016323647 |