Hepatocyte-specific expression of constitutively active Alk5 exacerbates thioacetamide-induced liver injury in mice

While Transforming growth factor-βs (Tgf-βs) have been known to play an important role in liver fibrosis through an activation of Hepatic Stellate Cells (HSC), their fibrotic role on hepatocytes in liver damage has not been addressed thoroughly. To shed more light on the hepatocyte-specific role of...

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Bibliographic Details
Main Authors: Wanthita Kongphat, Arnon Pudgerd, Somyoth Sridurongrit
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844016323647