Regulation of Fibroblast Growth Factor-2 Expression and Cell Cycle Progression by an Endogenous Antisense RNA

Regulation of Fibroblast Growth Factor-2 Expression and Cell Cycle Progression by an Endogenous Antisense RNA

Basic fibroblast growth factor (FGF2) is a potent wide-spectrum mitogen whose overexpression is associated with immortalization and unregulated cell proliferation in many tumors. The FGF2 gene locus is bi-directionally transcribed to produce FGF2 mRNA from the “sense” strand and a<em>...

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Bibliographic Details
Main Authors: Paul R. Murphy, Leigh Ann MacFarlane, Mark Baguma-Nibasheka
Format: Article
Language:English
Published: MDPI AG 2012-08-01
Series:Genes
Subjects:
antisense RNA
FGF2
NUDT6
siRNA
cell cycle
Online Access:http://www.mdpi.com/2073-4425/3/3/505

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