| Summary: | Cryptosporidiosis is currently recognized worldwide as a leading cause of moderate to severe diarrhea. In Europe, large water- and foodborne outbreaks have been reported, highlighting the widespread distribution of the parasite and its important health impact. Surveillance networks have been progressively set up and the aim of this study was to present recent epidemiological data obtained in France from 2017 to 2019 by the National Reference Center—Expert Laboratory of cryptosporidiosis (Centre National de Référence–Laboratoire Expert cryptosporidioses CNR-LE). Data were obtained from online reports of volunteer network participants and stools were sent to the CNR-LE for species identification and <i>GP60</i> genotyping. During this period, data from 750 online reports were available. Cryptosporidiosis occurred predominantly in young children (<5 years old) and in young adults, especially during late summer. Most patients were immunocompetent (60%), and deaths were reported only in immunocompromised patients. <i>Cryptosporidium parvum</i> was largely predominant (72% of cases) over<i> C. hominis</i> (24%) and some other uncommon species. <i>C. parvum GP60</i> subtypes IIa and IId were the most represented, which suggests frequent zoonotic transmission. For <i>C. hominis,</i> subtypes IbA10G2 and IaA22R2 were predominant.
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