Efficacy of pre-operative stereotactic radiosurgery followed by surgical resection and correlative radiobiological analysis for patients with 1–4 brain metastases: study protocol for a phase II trial

Efficacy of pre-operative stereotactic radiosurgery followed by surgical resection and correlative radiobiological analysis for patients with 1–4 brain metastases: study protocol for a phase II trial

Abstract Background Stereotactic radiosurgery (SRS) has emerged as a common adjuvant modality used with surgery for resectable brain metastases (BMs). However, the optimal sequence of the multi-modality therapy has not been established. The goal of the study is to evaluate 6-month local control util...

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Bibliographic Details
Main Authors: Wei X. Huff, Namita Agrawal, Scott Shapiro, James Miller, Charles Kulwin, Mitesh Shah, Jesse J. Savage, Troy Payner, Alexander Vortmeyer, Gordon Watson, Mahua Dey
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Radiation Oncology
Subjects:
Stereotactic radiosurgery
Brain metastases
Metastases surgery
Immune profiling
Molecular profiling
Online Access:http://link.springer.com/article/10.1186/s13014-018-1178-8

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