Endothelial cell-type-specific molecular requirements for angiogenesis drive fenestrated vessel development in the brain

Vascular endothelial cells (vECs) in the brain exhibit structural and functional heterogeneity. Fenestrated, permeable brain vasculature mediates neuroendocrine function, body-fluid regulation, and neural immune responses; however, its vascular formation remains poorly understood. Here, we show that...

Full description

Bibliographic Details
Main Authors: Sweta Parab, Rachael E Quick, Ryota L Matsuoka
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-01-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/64295