Trophoblast glycoprotein is a marker for efficient sorting of ventral mesencephalic dopaminergic precursors derived from human pluripotent stem cells

Abstract Successful cell therapy for Parkinson’s disease (PD) requires large numbers of homogeneous ventral mesencephalic dopaminergic (vmDA) precursors. Enrichment of vmDA precursors via cell sorting is required to ensure high safety and efficacy of the cell therapy. Here, using LMX1A-eGFP knock-in...

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Bibliographic Details
Main Authors: Jeong-Eun Yoo, Dongjin R. Lee, Sanghyun Park, Hye-Rim Shin, Kun Gu Lee, Dae-Sung Kim, Mi-Young Jo, Jang-Hyeon Eom, Myung Soo Cho, Dong-Youn Hwang, Dong-Wook Kim
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-021-00204-8