Calculating the Number of People with Alzheimer's Disease in any Country Using Saturated Mutation Models of Brain Cell Loss that also Predict Widespread Natural Immunity to the Disease

Calculating the Number of People with Alzheimer's Disease in any Country Using Saturated Mutation Models of Brain Cell Loss that also Predict Widespread Natural Immunity to the Disease

The series of mutations that cause brain cells to spontaneously and randomly die leading to Alzheimer's disease (AD) is modelled. The prevalence of AD as a function of age in males and females is calculated from two very different mutation models of brain cell death. Once the prevalence functio...

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Main Author: Ivan Kramer
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Computational and Mathematical Methods in Medicine
Online Access:http://dx.doi.org/10.1080/17486700902910076
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spelling doaj-45023ccb84374e07b769d189013141862020-11-25T01:00:55ZengHindawi LimitedComputational and Mathematical Methods in Medicine1748-670X1748-67182010-01-0111211915910.1080/17486700902910076Calculating the Number of People with Alzheimer's Disease in any Country Using Saturated Mutation Models of Brain Cell Loss that also Predict Widespread Natural Immunity to the DiseaseIvan Kramer0Department of Physics, University of Maryland Baltimore County, Catonsville, 1000 Hilltop Circle, MD 21250, USAThe series of mutations that cause brain cells to spontaneously and randomly die leading to Alzheimer's disease (AD) is modelled. The prevalence of AD as a function of age in males and females is calculated from two very different mutation models of brain cell death. Once the prevalence functions are determined, the number of people with AD in any country or city can be estimated.http://dx.doi.org/10.1080/17486700902910076
collection DOAJ
language English
format Article
sources DOAJ
author Ivan Kramer
spellingShingle Ivan Kramer
Calculating the Number of People with Alzheimer's Disease in any Country Using Saturated Mutation Models of Brain Cell Loss that also Predict Widespread Natural Immunity to the Disease
Computational and Mathematical Methods in Medicine
author_facet Ivan Kramer
author_sort Ivan Kramer
title Calculating the Number of People with Alzheimer's Disease in any Country Using Saturated Mutation Models of Brain Cell Loss that also Predict Widespread Natural Immunity to the Disease
title_short Calculating the Number of People with Alzheimer's Disease in any Country Using Saturated Mutation Models of Brain Cell Loss that also Predict Widespread Natural Immunity to the Disease
title_full Calculating the Number of People with Alzheimer's Disease in any Country Using Saturated Mutation Models of Brain Cell Loss that also Predict Widespread Natural Immunity to the Disease
title_fullStr Calculating the Number of People with Alzheimer's Disease in any Country Using Saturated Mutation Models of Brain Cell Loss that also Predict Widespread Natural Immunity to the Disease
title_full_unstemmed Calculating the Number of People with Alzheimer's Disease in any Country Using Saturated Mutation Models of Brain Cell Loss that also Predict Widespread Natural Immunity to the Disease
title_sort calculating the number of people with alzheimer's disease in any country using saturated mutation models of brain cell loss that also predict widespread natural immunity to the disease
publisher Hindawi Limited
series Computational and Mathematical Methods in Medicine
issn 1748-670X
1748-6718
publishDate 2010-01-01
description The series of mutations that cause brain cells to spontaneously and randomly die leading to Alzheimer's disease (AD) is modelled. The prevalence of AD as a function of age in males and females is calculated from two very different mutation models of brain cell death. Once the prevalence functions are determined, the number of people with AD in any country or city can be estimated.
url http://dx.doi.org/10.1080/17486700902910076
work_keys_str_mv AT ivankramer calculatingthenumberofpeoplewithalzheimersdiseaseinanycountryusingsaturatedmutationmodelsofbraincelllossthatalsopredictwidespreadnaturalimmunitytothedisease
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