Calculating the Number of People with Alzheimer's Disease in any Country Using Saturated Mutation Models of Brain Cell Loss that also Predict Widespread Natural Immunity to the Disease
The series of mutations that cause brain cells to spontaneously and randomly die leading to Alzheimer's disease (AD) is modelled. The prevalence of AD as a function of age in males and females is calculated from two very different mutation models of brain cell death. Once the prevalence functio...
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| Format: | Article |
| Language: | English |
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Hindawi Limited
2010-01-01
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| Series: | Computational and Mathematical Methods in Medicine |
| Online Access: | http://dx.doi.org/10.1080/17486700902910076 |
| Summary: | The series of mutations that cause brain cells to spontaneously and randomly die leading to Alzheimer's disease (AD) is modelled. The prevalence of AD as a function of age in males and females is calculated from two very different mutation models of brain cell death. Once the prevalence functions are determined, the number of people with AD in any country or city can be estimated. |
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| ISSN: | 1748-670X 1748-6718 |