DEVELOPMENT OF A NEW PROCESS FOR PURIFICATION OF CAPSULAR POLYSACCHARIDE FROM Streptococcus pneumoniae SEROTYPE 14

DEVELOPMENT OF A NEW PROCESS FOR PURIFICATION OF CAPSULAR POLYSACCHARIDE FROM Streptococcus pneumoniae SEROTYPE 14

Abstract The main virulence factor of Streptococcus pneumoniae is the capsular polysaccharide (PS), which is the antigen of all current vaccines that are prepared with PS purified from serotypes prevalent in the population. In this work, three purification strategies were evaluated and a new process...

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Bibliographic Details
Main Authors:	R. T. Zanardo, A. L. S. Ferri, D. B. Figueiredo, S. Kraschowetz, J. Cabrera-Crespo, V. M. Gonçalves
Format:	Article
Language:	English
Published:	Brazilian Society of Chemical Engineering
Series:	Brazilian Journal of Chemical Engineering
Subjects:	Pneumococcal vaccine Purification strategy Sodium dodecyl sulfate Trichloroacetic acid Anion exchange chromatography
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-66322016000300435&lng=en&tlng=en

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