Cholinoceptor Activation Subserving the Effects of Interferon Gamma on the Contractility of Rat Ileum

Recombinant rat interferon γ stimulated the contractility of isolated rat ileum at doses of 4–12 units/ml. Muscarinic cholinoceptors were involved, as treatment of the tissue with atropine prevented the contractile response of the ileum. Furthermore, interferon γ increased the affinity of carbachol...

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Bibliographic Details
Main Authors: Enri S. Borda, Leonor Sterin-Borda, Martin Rodriguez, Maria M. E. de Bracco
Format: Article
Language:English
Published: Hindawi Limited 1994-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/S0962935194000645