Tacrolimus inhibits the revascularization of isolated pancreatic islets.

AIMS: Immunosuppressive drugs could be crucial factors for a poor outcome after islet allotransplantation. Unlike rapamycin, the effects of tacrolimus, the current standard immunosuppressant used in islet transplantation, on graft revascularization remain unclear. We examined the effects of tacrolim...

Full description

Bibliographic Details
Main Authors: Ryuichi Nishimura, Sho Nishioka, Ikuma Fujisawa, Hitoshi Shiku, Miki Shimada, Satoshi Sekiguchi, Keisei Fujimori, Akira Ushiyama, Tomokazu Matsue, Noriaki Ohuchi, Susumu Satomi, Masafumi Goto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3629082?pdf=render