A novel network integrating a miRNA-203/SNAI1 feedback loop which regulates epithelial to mesenchymal transition.

A novel network integrating a miRNA-203/SNAI1 feedback loop which regulates epithelial to mesenchymal transition.

The majority of human cancer deaths are caused by metastasis. The metastatic dissemination is initiated by the breakdown of epithelial cell homeostasis. During this phenomenon, referred to as epithelial to mesenchymal transition (EMT), cells change their genetic and trancriptomic program leading to...

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Bibliographic Details
Main Authors: Michèle Moes, Antony Le Béchec, Isaac Crespo, Christina Laurini, Aliaksandr Halavatyi, Guillaume Vetter, Antonio Del Sol, Evelyne Friederich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3325969?pdf=render

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http://europepmc.org/articles/PMC3325969?pdf=render

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