miRNA profiles as a predictor of chemoresponsiveness in Wilms' tumor blastema.

miRNA profiles as a predictor of chemoresponsiveness in Wilms' tumor blastema.

The current SIOP treatment protocol for Wilms' tumor involves pre-operative chemotherapy followed by nephrectomy. Not all patients benefit equally from such chemotherapy. The aim of this study was to generate a miRNA profile of chemo resistant blastemal cells in high risk Wilms' tumors whi...

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Bibliographic Details
Main Authors: Jenny A Watson, Kenneth Bryan, Richard Williams, Sergey Popov, Gordan Vujanic, Aurore Coulomb, Liliane Boccon-Gibod, Norbert Graf, Kathy Pritchard-Jones, Maureen O'Sullivan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3538586?pdf=render

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